Autoimmune Hepatitis

Gastroenterology

Overview

Definition

Chronic inflammatory liver disease.

Epidemiology

Varies globally depending on genetics, environment, or exposure.

Etiology & Risk Factors

  • Autoimmune attack on hepatocytes.

Clinical Symptoms

  • Fatigue
  • jaundice
  • right upper quadrant discomfort.

Clinical Approach

Diagnosis

  • High AST/ALT
  • Anti-smooth muscle antibodies (ASMA)
  • High IgG.

Management

  • Corticosteroids (Prednisone) + Azathioprine.

Complications

  • Liver cirrhosis.