Glomerulonephritis

Nephrology

Overview

Definition

Inflammation of the tiny filters in the kidneys (glomeruli).

Epidemiology

Important cause of end-stage renal disease globally.

Etiology & Risk Factors

  • Post-streptococcal infection
  • Lupus
  • IgA Nephropathy
  • Anti-GBM disease

Clinical Symptoms

  • Hematuria (cola-colored urine)
  • Hypertension
  • Edema

Clinical Approach

Diagnosis

  • Urinalysis (RBC casts, proteinuria)
  • Renal biopsy

Management

  • Blood pressure control
  • Immunosuppressants
  • Plasmapheresis (if severe)

Complications

  • Acute Kidney Injury
  • Chronic Kidney Disease