Overview
Definition
Autoimmune destruction of the thyroid gland.
Epidemiology
Varies globally. Often age and lifestyle dependent.
Etiology & Risk Factors
- Autoimmune.
Clinical Symptoms
- Painless goiter
- symptoms of hypothyroidism (fatigue
- cold intolerance).
Clinical Approach
Diagnosis
- High TSH
- low Free T4
- Anti-TPO antibodies.
Management
- Levothyroxine.
Complications
- Myxedema coma
- Primary thyroid lymphoma.