Overview
Definition
Insulin-secreting tumor of the pancreas.
Epidemiology
Varies globally depending on genetics, environment, or exposure.
Etiology & Risk Factors
- Mostly benign, sporadic pancreatic neuroendocrine tumor.
Clinical Symptoms
- Whipple's triad: Fasting hypoglycemia
- Symptoms of hypoglycemia
- Relief with glucose.
Clinical Approach
Diagnosis
- Fasting hypoglycemia with inappropriately high insulin and high C-peptide.
Management
- Surgical enucleation/resection.
Complications
- Severe hypoglycemia
- coma.