Lung Cancer (Non-Small Cell)

Oncology

Overview

Definition

Most common type of lung cancer, including adenocarcinoma and squamous cell carcinoma.

Epidemiology

Leading cause of cancer death worldwide.

Etiology & Risk Factors

  • Tobacco smoking
  • Radon exposure
  • Asbestos

Clinical Symptoms

  • Chronic cough
  • Hemoptysis
  • Weight loss
  • Dyspnea

Clinical Approach

Diagnosis

  • CT Chest
  • Bronchoscopy with biopsy
  • PET scan for staging

Management

  • Surgical resection
  • Chemoradiation
  • Targeted therapy (EGFR/ALK)
  • Immunotherapy

Complications

  • Metastasis (Brain, Bone, Liver)
  • SVC Syndrome
  • Paraneoplastic syndromes