Thin Basement Membrane Disease

Nephrology

Overview

Definition

Benign familial hematuria.

Epidemiology

Varies globally depending on genetics, environment, or exposure.

Etiology & Risk Factors

  • Genetic defect in Type IV collagen.

Clinical Symptoms

  • Asymptomatic microscopic hematuria throughout life.

Clinical Approach

Diagnosis

  • Renal biopsy (extremely thin basement membrane).

Management

  • Reassurance
  • no treatment needed.

Complications

  • None (excellent prognosis).