Cephalexin (Keflex)

Antibiotic (1st Gen Cephalosporin)

Dosing & Administration

Adult Dose

500 mg PO every 6-12 hours.

Pediatric Dose

25-50 mg/kg/day PO divided every 6-8 hours.

Renal Adjustment

CrCl < 50: Max 500 mg every 12-24 hours.

Hepatic Adjustment

No adjustment necessary.

Safety & Special Populations

Pregnancy Category

B

Lactation Safety

Compatible.

Contraindications & Adverse Effects

Contraindications

  • Severe penicillin allergy (cross-reactivity)

Common Adverse Effects

  • Diarrhea
  • Dyspepsia
  • Rash