Insulin Glargine (Lantus / Toujeo)

Endocrinology (Long-acting Insulin)

Dosing & Administration

Adult Dose

Type 1: 1/3 to 1/2 of total daily insulin dose SQ once daily. Type 2: Start 10 units SQ daily.

Pediatric Dose

Type 1: Similar to adult proportion.

Renal Adjustment

Dose reduction may be required due to decreased insulin clearance.

Hepatic Adjustment

Dose reduction may be required.

Safety & Special Populations

Pregnancy Category

C - Generally considered safe and necessary.

Lactation Safety

Compatible.

Contraindications & Adverse Effects

Contraindications

  • During episodes of hypoglycemia

Common Adverse Effects

  • Hypoglycemia
  • Weight gain
  • Lipodystrophy at injection site