Dosing & Administration
Adult Dose
0.3 - 10 mcg/kg/min IV infusion.
Pediatric Dose
0.3 - 10 mcg/kg/min IV infusion.
Renal Adjustment
High risk of thiocyanate toxicity in renal failure.
Hepatic Adjustment
High risk of cyanide toxicity in hepatic failure.
Safety & Special Populations
Pregnancy Category
C
Lactation Safety
Unknown.
Contraindications & Adverse Effects
Contraindications
- Compensatory hypertension (e.g., A-V shunt or coarctation)
Common Adverse Effects
- Severe hypotension
- Cyanide toxicity
- Thiocyanate toxicity