Normal Reference Ranges
Adult
< 1.0 (Negative) Index
Pediatric
N/A Index
Clinical Significance
Antibody targeting histidyl-tRNA synthetase. High specificity for inflammatory myopathies and antisynthetase syndrome (characterized by interstitial lung disease, arthritis, and mechanic's hands).
Causes of High
- Polymyositis
- Dermatomyositis
- Antisynthetase syndrome
Causes of Low
- Normal finding