Normal Reference Ranges
Adult
0.7 - 2.0 mg/L
Pediatric
0.7 - 2.0 mg/L
Clinical Significance
Light chain component of HLA-Class I molecules. Serves as a major prognostic marker in multiple myeloma and chronic lymphocytic leukemia.
Causes of High
- Multiple myeloma
- Lymphomas (CLL, NHL)
- Renal failure
- Chronic inflammation / viral infections
Causes of Low
- Normal finding