Normal Reference Ranges
Adult
0.1 - 1.2 mg/dL
Pediatric
0.2 - 1.0 (Higher in newborns) mg/dL
Clinical Significance
Breakdown product of hemoglobin. >2.5-3.0 mg/dL typically results in clinical jaundice or icterus.
Causes of High
- Hemolysis (unconjugated)
- Biliary obstruction (conjugated)
- Hepatitis
- Cirrhosis
- Gilbert's syndrome
Causes of Low
- Normal finding