Normal Reference Ranges
Adult
Male: < 8.4 | Female: < 5.0 pg/mL
Pediatric
N/A pg/mL
Clinical Significance
Hormone secreted by parafollicular C-cells of the thyroid. Highly specific tumor marker for medullary thyroid cancer and monitoring of patients with MEN2 syndrome.
Causes of High
- Medullary Thyroid Carcinoma (MTC)
- C-cell hyperplasia
- Chronic renal failure
- Leukemia
Causes of Low
- Normal finding