Normal Reference Ranges
Adult
< 50 mcg/g
Pediatric
< 50 mcg/g
Clinical Significance
Neutrophil-derived protein in stool. Excellent non-invasive test to differentiate IBD (elevated) from IBS (normal).
Causes of High
- Inflammatory Bowel Disease (Crohn's, Ulcerative Colitis)
- Bacterial gastroenteritis
- NSAID enteropathy
Causes of Low
- Irritable Bowel Syndrome (IBS)
- Normal finding