Normal Reference Ranges
Adult
< 200 mg/dL
Pediatric
< 170 mg/dL
Clinical Significance
Used to assess the risk of cardiovascular disease. Must be evaluated alongside HDL, LDL, and triglycerides.
Causes of High
- Familial hypercholesterolemia
- Diet high in saturated fats
- Hypothyroidism
- Nephrotic syndrome
- Biliary cirrhosis
Causes of Low
- Severe liver disease
- Malnutrition
- Hyperthyroidism