Normal Reference Ranges
Adult
0 - 3 (or < 5% of total CK) ng/mL
Pediatric
0 - 3 ng/mL
Clinical Significance
Isoenzyme of CK more specific to cardiac muscle. Peaks in 24 hrs and normalizes in 48-72 hrs, useful for detecting re-infarction (unlike troponin).
Causes of High
- Acute Myocardial Infarction
- Myocarditis
- Cardiac contusion/surgery
Causes of Low
- Normal finding