Normal Reference Ranges
Adult
< 500 (or Age × 10 for > 50 yrs) ng/mL (FEU)
Pediatric
< 500 ng/mL (FEU)
Clinical Significance
Fibrin degradation product. Highly sensitive but poorly specific. Excellent for ruling out PE/DVT in low-probability patients.
Causes of High
- Pulmonary Embolism (PE)
- Deep Vein Thrombosis (DVT)
- DIC
- Pregnancy
- Surgery/Trauma
- Malignancy
Causes of Low
- Normal finding