Normal Reference Ranges
Adult
8.6 - 18.6 U/g Hb
Pediatric
8.6 - 18.6 U/g Hb
Clinical Significance
Measures glucose-6-phosphate dehydrogenase enzyme level. Low levels predispose red blood cells to oxidative stress and acute hemolytic anemia triggered by fava beans, infections, or drugs (e.g., primaquine, dapsone).
Causes of High
- Reticulocytosis (acute phase of hemolysis)
Causes of Low
- G6PD Deficiency (X-linked genetic mutation)