Normal Reference Ranges
Adult
Negative Qualitative
Pediatric
Negative Qualitative
Clinical Significance
Indicates exposure to HBV. Positive in both active and resolved infection, but NOT positive following vaccination alone (since vaccine contains only surface antigen).
Causes of High
- Acute Hepatitis B infection
- Chronic Hepatitis B infection
- Resolved past Hepatitis B infection (exposed)
Causes of Low
- No exposure to Hepatitis B (Normal)