HIV-1/2 Ag/Ab Combo (4th Gen)

Infectious Disease

Normal Reference Ranges

Adult

Non-Reactive (Negative) Index

Pediatric

Non-Reactive (Negative) Index

Clinical Significance

Standard screening test for HIV. Detects both the p24 viral antigen (early infection) and HIV antibodies (later infection). Reactive results require confirmatory differentiation testing.

Causes of High

  • Acute HIV Infection (p24 Antigen positive)
  • Chronic HIV Infection (Antibody positive)
  • Rare false positive (Autoimmune, Pregnancy)

Causes of Low

  • Normal finding