Luteinizing Hormone (LH)

Endocrine & Reproductive

Normal Reference Ranges

Adult

Male: 1.2-8.6 | Female: Varies (Spikes at ovulation) mIU/mL

Pediatric

Varies by age/Tanner stage mIU/mL

Clinical Significance

Triggers ovulation and corpus luteum development in females, and stimulates Leydig cells to produce testosterone in males.

Causes of High

  • Primary gonadal failure
  • Polycystic Ovary Syndrome (PCOS - high LH/FSH ratio)

Causes of Low

  • Pituitary failure
  • Severe stress/malnutrition (Functional hypothalamic amenorrhea)