Normal Reference Ranges
Adult
Negative Qualitative
Pediatric
Negative Qualitative
Clinical Significance
An antibody that prolongs phospholipid-dependent clotting tests in vitro but is strongly associated with an increased risk of thrombosis (arterial and venous) and recurrent miscarriages in vivo.
Causes of High
- Antiphospholipid Syndrome (APS)
- Systemic Lupus Erythematosus (SLE)
- Drug-induced antibodies
Causes of Low
- Normal finding