Normal Reference Ranges
Adult
< 0.15 ng/mL
Pediatric
< 0.15 ng/mL
Clinical Significance
Highly specific biomarker for systemic bacterial infections. Used to guide initiation and cessation of antibiotic therapy.
Causes of High
- Bacterial sepsis
- Severe localized bacterial infection
- Major trauma/surgery
- Severe burns
Causes of Low
- Viral infection
- Normal finding