Normal Reference Ranges
Adult
0.5 - 1.5 %
Pediatric
0.5 - 2.0 %
Clinical Significance
Measures immature red blood cells. Crucial for distinguishing between hypoproliferative anemias (low count) and destructive/loss anemias (high count).
Causes of High
- Hemolytic anemia
- Acute blood loss
- Response to therapy (Iron, B12, Folate replacement)
Causes of Low
- Aplastic anemia
- Untreated iron/B12 deficiency
- Bone marrow suppression
- Chronic kidney disease (low EPO)