Normal Reference Ranges
Adult
< 14 IU/mL
Pediatric
< 14 IU/mL
Clinical Significance
Autoantibody typically targeting the Fc portion of IgG. Used to help diagnose Rheumatoid Arthritis, though anti-CCP is more specific.
Causes of High
- Rheumatoid Arthritis
- Sjögren's syndrome
- Lupus (SLE)
- Chronic infections (Hepatitis C, Endocarditis)
Causes of Low
- Normal finding