Rapid Plasma Reagin (RPR)

Infectious Disease

Normal Reference Ranges

Adult

Non-Reactive Titer

Pediatric

Non-Reactive Titer

Clinical Significance

Non-treponemal screening test for Syphilis. Also used to track the efficacy of treatment (titers should decrease by 4-fold).

Causes of High

  • Active Syphilis (Treponema pallidum)
  • False positive (Lupus, Pregnancy, acute viral illness)

Causes of Low

  • Normal finding
  • Successfully treated Syphilis (titer drops)