Normal Reference Ranges
Adult
< 4.0 U/mL (Negative) U/mL
Pediatric
< 4.0 U/mL (Negative) U/mL
Clinical Significance
Highly sensitive and specific serologic screening test for Celiac disease. Total IgA must be measured concurrently to rule out IgA deficiency.
Causes of High
- Celiac Disease
- Dermatitis herpetiformis
Causes of Low
- Normal finding
- False negative in patients with selective IgA deficiency