Normal Reference Ranges
Adult
20 - 275 mg/dL
Pediatric
Varies by muscle mass mg/dL
Clinical Significance
Used as a reference marker to normalize other random urine analytes (e.g. Urine Protein-to-Creatinine Ratio).
Causes of High
- Concentrated urine (dehydration)
Causes of Low
- Dilute urine (fluid overload)
- Severe muscle wasting