Normal Reference Ranges
Adult
10.0 - 20.0 (Target dependent on infection severity) mcg/mL
Pediatric
Same as adult mcg/mL
Clinical Significance
Ensures therapeutic efficacy and limits nephrotoxicity in treating serious MRSA or enterococcal infections.
Causes of High
- Renal clearance impairment
- Vancomycin overdose
Causes of Low
- Subtherapeutic dosing
- Augmented renal clearance