Ventilator Reference Library

Comprehensive guide to ventilator modes and waveform analysis.

Volume Control Ventilation (VCV / AC-VC)

Mechanism

The ventilator delivers a preset tidal volume at a set rate. If the patient triggers a breath, they receive the full preset tidal volume.

Indications

Initial mode for most critically ill patients requiring full ventilatory support.

Advantages

Guarantees a specific minute ventilation and tidal volume.

Limitations

Peak inspiratory pressures can vary greatly. Can lead to patient-ventilator asynchrony if the patient's flow demand is higher than set flow.

Pressure Control Ventilation (PCV / AC-PC)

Mechanism

The ventilator delivers a breath at a preset inspiratory pressure for a preset inspiratory time.

Indications

Patients with poor lung compliance (ARDS) to limit peak alveolar pressures and prevent barotrauma.

Advantages

Limits peak pressures, preventing barotrauma. Better flow synchronization as the flow is decelerating and variable based on patient demand.

Limitations

Tidal volume is variable. Minute ventilation is not guaranteed and can drop if lung compliance worsens.

Synchronized Intermittent Mandatory Ventilation (SIMV)

Mechanism

Delivers a set number of mandatory breaths synchronized with the patient's effort, but allows the patient to take spontaneous, unsupported (or pressure-supported) breaths in between.

Indications

Weaning, or for patients who need partial support.

Advantages

Prevents breath stacking. Exercises respiratory muscles.

Limitations

May increase work of breathing if mandatory rate is too low. Generally falling out of favor compared to PSV for weaning.

Pressure Regulated Volume Control (PRVC)

Mechanism

A dual-control mode. The ventilator attempts to achieve a target tidal volume by automatically adjusting the inspiratory pressure breath-by-breath.

Indications

Patients whose compliance is changing rapidly, to guarantee volume while minimizing pressure.

Advantages

Combines the benefits of VCV (guaranteed volume) and PCV (decelerating flow, pressure limit).

Limitations

If patient effort increases significantly, the ventilator may paradoxically decrease support to maintain the target volume, causing air hunger.

Pressure Support Ventilation (PSV)

Mechanism

A purely spontaneous mode. Every breath is initiated and terminated by the patient, but the ventilator provides a set pressure during inspiration to overcome airway resistance.

Indications

Weaning trials (SBTs), overcoming endotracheal tube resistance in spontaneously breathing patients.

Advantages

Very comfortable for the patient. Allows patient to control rate, inspiratory time, and tidal volume.

Limitations

No backup rate. Patient must have a reliable respiratory drive.

Airway Pressure Release Ventilation (APRV)

Mechanism

Inverse ratio ventilation using two levels of CPAP (Phigh and Plow) with brief releases to Plow to facilitate CO2 clearance.

Indications

Severe ARDS failing conventional lung-protective ventilation.

Advantages

Maximizes mean airway pressure for oxygenation (alveolar recruitment) while allowing spontaneous breathing.

Limitations

Complex to manage. Requires an expert team. High risk of pneumothorax if not carefully monitored.